What we do

Our laboratory is equipped with specialised HPLC and  LC/MS/MS equipment, and we have a considerable library of methods for the analysis of pharmaceuticals and environmental toxins in biological fluids and medical infusions (see validated assays tab).  

We are highly experienced in the method development and validation of de novo LC and sample extraction methods - please enquire if this is required.

We are additionally happy to develop and perform stability-indicating LC analyses to investigate any issues of drug stability, new drug formulations and new drug combinations.

We can advise on developing pragmatic sampling schemes for pharmacokinetic studies, designed to enhance the robustness of the resulting pharmacokinetic parameter estimates.  This maximises the amount of kinetic information that can be gained from blood sampling regimes (and allows for the use of sparse sampling regimes).

We use NONMEM version 7 (the industry gold standard) and PLT Tools software for constructing mixed-effects models .  As well as providing a statistically superior method of analysis, mixed effects modelling can deal with practical problems that may occur frequently in pharmacokinetic studies, such as missed blood samples.

                  USP: We can offer a clinical trial one-stop-shop for local studies: 
     study design, sample collection/storage and sample/pharmacokinetic analysis


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Contact us:

Phone: 00-44-(0)1752-432014

Email: info@c3pa.co.uk

Post:
C3P Analysis, ITTC Building,
Plymouth Science Park, Davy Rd,
Plymouth, Devon
PL6 8BX